|
KMID : 0613820200300030298
|
|
Journal of Life Science
2020 Volume.30 No. 3 p.298 ~ p.303
|
|
|
Antimicrobial, Antioxidant, and Anti-diabetic Activities of Rodgersia podophylla
|
|
Pyo Su-Jin
Lee Yun-Jin
Kang Deok-Gyeong
Son Ho-Jun
Park Gwang-Hun
Park Jong-Yi
Sohn Ho-Yong
|
|
|
Abstract
|
|
|
|
This study aimed to investigate possible applications of Rodgersia podophylla in the food and cosmetic industry. Ethanol extracts of leaves (RP-L), branches (RP-B), and root (RP-R) were prepared, and their antimicrobial, antioxidant, and anti-diabetic activities were evaluated. The polyphenol content in the RP-R, RP-L, and RP-B extracts was 79.6, 30.4, and 16.9 mg/g, respectively. An antimicrobial activity assay showed that the RP-L and RP-R extracts exhibited strong growth inhibition of pathogenic and food spoilage Gram-positive bacteria. Furthermore, the RP-R extract inhibited the growth of the Gram- negative E. coli and P. vulgaris bacteria. All extracts showed strong scavenging activity for DPPH, ABTS, nitrite, and reducing power determined by A 700 nm. In particular, the RC50s of the RP-R extract for the DPPH anion and ABTS cation were 23.0-29.7 and 15.0-18.2 μg/ml, respectively, which are comparable to those of vitamin C (9.8 and 8.0 μg/ml, respectively). An activity assay of α-glucosidase and β-amylase suggested a high potential for the RP-R extract as an anti-diabetic agent. Its inhibition levels of α-glucosidase and β-amylase at 0.5 mg/ml were 6.9 and 48.5%, respectively. This is the first report of the antimicrobial and anti-diabetic activities of R. podophylla. Our results suggest that RP-L and RP-R extracts could be developed as novel cosmeceutical and functional food resources.
|
|
|
KEYWORD
|
|
|
Anti-diabetes, antimicrobial, antioxidant, Rodgersia podophylla
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|